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Non-genomic effects of estrogen in endometrial stromal cell lines and primary cultures

The aim of the project is to clarify the function of the non-genomic estrogen action in pathogenesis of endometriosis. In particular our goal is:

  • To identify signal transduction pathways regulated by fast estrogen receptors-mediated signals
  • To specify estrogen receptors subtypes (classical and non-classical) involved in this regulations.
  • To provide the molecular mechanisms involved in the non-genomic estrogen action.

 

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